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Gianluca Tell Selected Research

DNA-(Apurinic or Apyrimidinic Site) Lyase (AP Endonuclease)

1/2021Enzymatically active apurinic/apyrimidinic endodeoxyribonuclease 1 is released by mammalian cells through exosomes.
1/2019Serum AP-endonuclease 1 (sAPE1) as novel biomarker for hepatocellular carcinoma.
3/2014Expression and prognostic significance of APE1/Ref-1 and NPM1 proteins in high-grade ovarian serous cancer.
11/2010Understanding different functions of mammalian AP endonuclease (APE1) as a promising tool for cancer treatment.

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Gianluca Tell Research Topics

Disease

37Neoplasms (Cancer)
06/2021 - 03/2002
8Genomic Instability
01/2021 - 02/2014
7Thyroid Neoplasms (Thyroid Cancer)
06/2009 - 03/2002
6Carcinoma (Carcinomatosis)
01/2017 - 03/2002
4Breast Neoplasms (Breast Cancer)
07/2019 - 01/2002
4Carcinogenesis
02/2014 - 03/2006
3Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2020 - 01/2013
3Triple Negative Breast Neoplasms
07/2019 - 04/2012
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2018 - 08/2004
3Liver Diseases (Liver Disease)
01/2015 - 07/2004
3Osteoporosis
06/2011 - 10/2006
3Ischemia
06/2006 - 07/2004
2Hepatocellular Carcinoma (Hepatoma)
11/2020 - 01/2019
2Reperfusion Injury
01/2019 - 06/2006
2Inflammation (Inflammations)
01/2019 - 01/2018
2Osteosarcoma (Osteogenic Sarcoma)
01/2018 - 05/2008
2Pre-Eclampsia (Preeclampsia)
08/2016 - 01/2007
2Anaplastic Thyroid Carcinoma
09/2008 - 04/2007
1Lung Neoplasms (Lung Cancer)
01/2021
1Colonic Neoplasms (Colon Cancer)
10/2019
1End Stage Liver Disease
01/2019
1Portal Hypertension
01/2019
1Pain (Aches)
01/2018
1Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
11/2016
1Neuroblastoma
09/2016
1Fetal Growth Retardation (Intrauterine Growth Retardation)
08/2016
1HELLP Syndrome
08/2016
1Hemolysis
08/2016
1Fibrosis (Cirrhosis)
01/2015
1Neurodegenerative Diseases (Neurodegenerative Disease)
05/2014
1Neoplasm Metastasis (Metastasis)
03/2014
1Liver Neoplasms (Liver Cancer)
01/2013
1Kernicterus
04/2010
1Alzheimer Disease (Alzheimer's Disease)
12/2009
1Bone Resorption
01/2009
1Bone Diseases (Bone Disease)
01/2009
1Postmenopausal Osteoporosis
09/2007

Drug/Important Bio-Agent (IBA)

33Proteins (Proteins, Gene)FDA Link
01/2021 - 01/2002
9EndonucleasesIBA
10/2019 - 03/2006
7NucleophosminIBA
01/2020 - 07/2010
6RNA (Ribonucleic Acid)IBA
06/2021 - 12/2010
6Biomarkers (Surrogate Marker)IBA
01/2021 - 02/2009
6EnzymesIBA
01/2021 - 02/2014
6Messenger RNA (mRNA)IBA
01/2015 - 03/2002
5DNA (Deoxyribonucleic Acid)IBA
01/2021 - 09/2005
4DNA-(Apurinic or Apyrimidinic Site) Lyase (AP Endonuclease)IBA
01/2021 - 11/2010
4Transcription Factors (Transcription Factor)IBA
01/2019 - 03/2003
3MicroRNAs (MicroRNA)IBA
01/2021 - 04/2012
3PlatinumIBA
07/2019 - 03/2014
3E 3330IBA
01/2018 - 01/2013
3Diphosphonates (Bisphosphonates)IBA
06/2011 - 10/2006
2Pharmaceutical PreparationsIBA
01/2021 - 09/2008
2Biological ProductsIBA
01/2021 - 10/2007
2A-Form DNA (A-DNA)IBA
10/2017 - 10/2013
2NitrogenIBA
06/2011 - 01/2009
2Reactive Oxygen Species (Oxygen Radicals)IBA
12/2009 - 09/2007
2NF-kappa B (NF-kB)IBA
09/2008 - 04/2007
2Adenosine Triphosphate (ATP)IBA
05/2008 - 10/2006
2sodium-iodide symporter (sodium iodide symporter)IBA
09/2005 - 03/2004
1Doxorubicin (Adriamycin)FDA LinkGeneric
11/2020
1DNA Transposable Elements (Element, IS)IBA
01/2020
1DNA Repair EnzymesIBA
01/2020
1Platinum Compounds (Compounds, Platinum)IBA
07/2019
1Hormones (Hormone)IBA
07/2019
1SaltsIBA
07/2019
1Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
01/2019
1Immunoglobulin A (IgA)IBA
01/2019
14-(3-chlorophenylsulfanyl)piperidineIBA
01/2019
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2018
1Freund's AdjuvantIBA
01/2018
1Tyrosine Kinase InhibitorsIBA
01/2018
1Mitochondrial DNA (mtDNA)IBA
01/2017
1Cell ExtractsIBA
11/2016
1Peptides (Polypeptides)IBA
09/2016
1Sirtuin 1IBA
02/2014
1CytokinesIBA
01/2013
1Interleukin-8 (Interleukin 8)IBA
01/2013
1Lysine (L-Lysine)FDA Link
07/2012
1BilirubinIBA
04/2010
1Amyloid beta-PeptidesIBA
12/2009
1Small Interfering RNA (siRNA)IBA
06/2009
12- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA
06/2009
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
06/2009
1AntioxidantsIBA
02/2009
1Conditioned Culture MediaIBA
09/2008
1IronIBA
09/2008
1AgarIBA
09/2008
1Purinergic Receptors (Receptors, Purine)IBA
05/2008
1Suramin (Suramin Sodium)IBA
05/2008
1Uridine Triphosphate (UTP)IBA
05/2008
1CalciumIBA
05/2008
1Apyrase (ATP Diphosphatase)IBA
05/2008
1Adenosine Diphosphate (ADP)IBA
05/2008
1Glucosylceramides (Glucocerebrosides)IBA
07/2007

Therapy/Procedure

9Therapeutics
01/2020 - 07/2004
4Drug Therapy (Chemotherapy)
11/2020 - 11/2010
4Liver Transplantation
01/2019 - 07/2004
1Precision Medicine
06/2021
1Spinal Injections
01/2018
1Ovariectomy (Oophorectomy)
09/2007